John H. Krystal, M.D., of Yale University received the BBRF Colvin Prize for Outstanding Achievement in Mood Disorders Research and presented at the Brain & Behavior Research Foundation 2019 International Mental Health Research Symposium in New Yo...

Ketamine just might save your life one day but nothing’s gunna save you from the hat man.. • Follow for daily content 🤘 • • • #ems #festival #rave #humor by whatsgood24.7.365

Hamilton odkrywa zaskakujące nowe sposoby użycia ketaminy na całym świecie. Zmierza do Indii by zobaczyć przemysłową syntezę i porozmawiać z terapeutami i luminarzami w próbie zrozumienia roli dysocjacyjnych anestetyków w społeczeństwie.

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"Ketamine has been found to be a rapid-acting antidepressant in depression, for instance in major depressive disorder, treatment-resistant depression, and bipolar depression. It also may be effective in rapidly alleviating suicidal ideation, although based on lower quality evidence. The rapid-onset antidepressant effects of ketamine were first shown in small studies in 2000 and 2006. They have since been demonstrated and characterized in subsequent studies. A single low, sub-anesthetic dose of ketamine given via intravenous infusion may produce antidepressant effects within four hours in people with depression. These antidepressant effects persist for at least a week following a single infusion. This is in contrast to conventional antidepressants like selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs), which generally require at least several weeks for their benefits to occur and become maximal. Moreover, based on the available preliminary evidence, the magnitude of the antidepressant effects of ketamine appears to be more than double that of conventional antidepressants. On the basis of these findings, a 2017 review described ketamine as the single most important advance in the treatment of depression in over 50 years. It has sparked interest in NMDA receptor antagonists for depression, and has shifted the direction of antidepressant research and development." - wikipedia

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